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VETERINARY · MOLECULAR DIAGNOSTICS

YS-M4

Compact real-time PCR quantitative system for focused veterinary molecular testing. The 750 g platform combines four fluorescence channels, fast thermal performance, touchscreen operation and Wi-Fi connectivity.

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YS-M4 real-time PCR system
01

Ultra-compact

Approximately 750 g with a 120 × 120 mm footprint.

02

Four channels

Supports FAM, HEX, ROX and CY5 fluorescence detection.

03

Fast thermal control

Maximum ramp rate up to 10°C per second.

04

Connected workflow

Integrated 4-inch touchscreen and Wi-Fi connectivity.

A CLOSER LOOK

Simple, single-tube handling

See the lid and loading chamber in detail.
YS-M4 navy and white instrument with lid closed and gloved hand above

Compact, top-access design

A close-up of the lid and compact instrument body, finished in the YSENZ VET family colors.

Gloved hand placing one clear PCR tube into the central YS-M4 sample well

Load one prepared PCR tube

Place the prepared tube into the central well, close the lid and start the assay-specific program.

Detail photographs have been retouched to show the YSENZ VET color and branding configuration. Final supplied appearance may vary.

TWO SAMPLE-TO-RESULT OPTIONS

Flexible molecular workflows

Choose an extraction-free workflow for speed or an AC20 extraction workflow when a separate nucleic-acid extraction step is required.

DIRECT WORKFLOW

Extraction-free one-step method

  1. 01
    Collect & mixCollect the pet sample directly into a prefilled tube containing extraction-free buffer. Mix and wait approximately 5 minutes.
  2. 02
    DispenseInvert the tube and press the blue bottom button to dispense 25 μL of sample into the prealiquoted lyophilized PCR reagent.
  3. 03
    Quick spinCentrifuge for 10 seconds to bring the reaction mixture to the bottom of the tube.
  4. 04
    AmplifyLoad the prepared tube into YS-M4 and run the selected real-time PCR program.

AC20 WORKFLOW

Method with nucleic-acid extraction

  1. 01
    Collect sampleCollect the appropriate swab, blood, stool or other validated specimen for the selected assay.
  2. 02
    Extract on AC20Add 200 μL of sample to the prefilled extraction reagent and complete nucleic-acid extraction on AC20.
  3. 03
    Quick spinCentrifuge the prepared reaction tube for 10 seconds.
  4. 04
    AmplifyTransfer 25 μL of prepared sample to the PCR reagent, load it into YS-M4 and start amplification.

Workflow volumes and specimen types must follow the instructions for the selected assay. Assay availability and performance specifications may vary by market.

VETERINARY NUCLEIC-ACID TESTING

Pet molecular assay menu

Single-target and multiplex options for common canine, feline and zoonotic pathogens.

Core single-target assays

  • Canine parvovirus (CPV)
  • Canine distemper virus (CDV)
  • Canine adenovirus (CAV; generic, type 1 and type 2 options)
  • Canine parainfluenza virus (CPIV)
  • Canine coronavirus (CCoV)
  • Feline coronavirus (FCoV)
  • Toxoplasma gondii
  • Bordetella bronchiseptica
  • Mycoplasma spp.
  • Mouse hepatitis virus (MHV)
  • Giardia lamblia
  • Cryptosporidium spp.
  • Tritrichomonas foetus
  • Rickettsia spp.
  • Bartonella henselae
  • Feline hemotropic Mycoplasma
  • Canine Mycoplasma

Feline panels

  • Feline respiratory 5-panel: Mycoplasma spp., Chlamydia felis, Bordetella bronchiseptica, feline calicivirus and feline herpesvirus type 1
  • Feline diarrhea 5-panel: FCoV, feline panleukopenia virus, Giardia, Cryptosporidium and Tritrichomonas foetus
  • FCoV + feline panleukopenia virus duplex
  • Feline diarrhea 4-panel: FCoV, feline panleukopenia virus, Giardia and Tritrichomonas foetus

Canine & zoonotic panels

  • Canine respiratory 6-panel: CDV, canine influenza virus, CPIV, canine Mycoplasma, CAV-2 and Bordetella bronchiseptica
  • Canine diarrhea 4-panel: canine coronavirus, canine parvovirus, Giardia and Tritrichomonas foetus
  • Zoonotic 6-panel: Toxoplasma gondii, Leptospira, Giardia, Rickettsia, Bartonella henselae and feline hemotropic Mycoplasma

Typical formats include lyophilized or liquid reagents. Pack sizes and regulatory status vary by market. Additional exotic-pet assays are under development.

ADDITIONAL REAGENT OPTIONS

Explore a broader veterinary menu

Selected research-use PCR reagent options, organized by species. These are separate from the existing pet assay menu above.

These additional reagent options are supplied for research use only. Listing does not establish validation on YS-M4. Confirm instrument compatibility, channel configuration, extraction requirements and the current assay instructions before ordering. Results must not be used as the sole basis for clinical diagnosis.

Companion-animal reagent details

Feline coronavirus (FCoV)

Listed specimens: EDTA whole blood, thoracic or abdominal fluid, feces

Listed channels: FAM / VIC

Endogenous internal control. Assay-specific preparation and YS-M4 compatibility require confirmation.

Chlamydia felis

Listed specimens: Eye and nasal secretions

Listed channels: FAM / VIC

Endogenous internal control. Assay-specific preparation and YS-M4 compatibility require confirmation.

Cattle, sheep & goats13 selected options
  • Brucella spp.
  • Peste des petits ruminants virus (PPRV)
  • Bovine viral diarrhea virus (BVDV): universal, type 1 and type 2 options
  • Sheeppox / goatpox virus
  • Lumpy skin disease virus (LSDV)
  • Akabane virus
  • Mycobacterium avium subsp. paratuberculosis (MAP)
  • Bluetongue virus
  • Mycoplasma bovis
  • Mycoplasma mycoides (contagious bovine pleuropneumonia)
  • Bovine herpesvirus 1 (infectious bovine rhinotracheitis)
  • Border disease virus
  • Bovine ephemeral fever virus
Equine5 selected options
  • African horse sickness virus
  • Eastern equine encephalitis virus
  • Equine infectious anemia virus
  • Equine piroplasms
  • Getah virus
Swine20 selected options
  • African swine fever virus (ASFV), including gene-target combinations
  • Porcine reproductive and respiratory syndrome virus (PRRSV), including strain and multiplex options
  • Classical swine fever virus
  • Porcine epidemic diarrhea virus (PEDV)
  • Transmissible gastroenteritis virus (TGEV)
  • Porcine rotavirus group A
  • Porcine deltacoronavirus
  • PEDV / TGEV / rotavirus multiplex
  • Porcine circovirus types 2, 3 and 4
  • Foot-and-mouth disease virus: universal, O, A and Asia 1 options
  • Pseudorabies virus: gH, gB, gE and combinations
  • Porcine parvovirus
  • Mycoplasma hyopneumoniae
  • Streptococcus suis, including type 2
  • Senecavirus A
  • Glaesserella parasuis (Haemophilus parasuis)
  • Influenza A and swine H1 / H3 / H1N1-2009 options
  • Actinobacillus pleuropneumoniae
  • Lawsonia intracellularis
  • Pathogenic Leptospira
Poultry & other birds20 selected options
  • Avian influenza A: H5, H7, H9 and multiplex options
  • Avian leukosis virus and subgroup options
  • Newcastle disease virus
  • Infectious bronchitis virus
  • Infectious laryngotracheitis virus
  • Infectious bursal disease virus
  • Avian reovirus
  • Mycoplasma gallisepticum / Mycoplasma synoviae
  • Duck plague virus
  • Salmonella spp., including Gallinarum, Pullorum and Enteritidis
  • Fowl adenovirus group I and types 4, 8b and 11
  • Marek's disease virus
  • Duck hepatitis A virus types 1, 2 and 3
  • Goose and Muscovy duck parvovirus
  • Duck Tembusu virus
  • Goose astrovirus
  • Avian metapneumovirus
  • Egg drop syndrome virus
  • Chicken infectious anemia virus
  • Fowlpox virus
Fish & shrimp22 selected options
  • Enterocytozoon hepatopenaei (EHP)
  • Vibrio harveyi
  • White spot syndrome virus (WSSV)
  • Acute hepatopancreatic necrosis disease (AHPND / EMS)
  • Shrimp hemocyte iridescent virus (SHIV / DIV1)
  • Taura syndrome virus
  • Siniperca chuatsi rhabdovirus
  • Largemouth bass virus / ulcerative syndrome virus
  • Infectious spleen and kidney necrosis virus (ISKNV)
  • Frog virus 3
  • Infectious hypodermal and hematopoietic necrosis virus (IHHNV)
  • Infectious myonecrosis virus
  • Yellow head virus
  • Singapore grouper iridovirus
  • Spring viremia of carp virus
  • Viral nervous necrosis virus
  • Carp pox virus (CyHV-1)
  • Cyprinid herpesvirus 2 (CyHV-2)
  • Koi herpesvirus (CyHV-3)
  • Grass carp reovirus types 1, 2 and 3
  • Vibrio spp. / Vibrio parahaemolyticus
  • Selected EHP, Vibrio, EMS and WSSV combination panels

This is a selected portfolio, not a complete list of every strain or panel configuration. The source includes extraction-based reagents; the extraction-free workflow is not applicable to every assay. Fluorescence-channel overlap alone does not demonstrate compatibility. Ask us to confirm the appropriate reagent, program and workflow for your application.

TECHNICAL DATA

Specifications

Throughput
1 sample per run
Consumable
0.2 mL thin-walled transparent single tube
Reaction system
15-100 μL
Temperature control
Peltier cooler; tube control
Maximum ramp rate
10°C/sec
Control accuracy
±0.1°C
Uniformity
±0.2°C
Heated lid
30-110°C adjustable; default 105°C
Fluorescence channels
FAM/SYBR Green I, HEX/VIC/JOE/TET, ROX, CY5
Dimensions
120 × 120 × 140 mm
Power
DC 12 V, 80 W
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